Echo flow versus (non-)invasive haemodynamics 2
- Conditions
- Adult patients (>18y), scheduled for coronary arterial bypass graft surgery and/or mono valve surgery
- Registration Number
- NL-OMON22829
- Lead Sponsor
- Amsterdam UMC location AMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 18
To be eligible to participate in this study, a subject must meet all of the following criteria:
-Adult patient (age > 18 years)
-Elective coronary arterial bypass graft surgery and/or mono valve surgery
-Informed consent
A subject who meets any of the following criteria will be excluded from participation in this study:
-Significant aortic valve stenosis > 30% without indication for valve repair, or abnormal anatomy of aortic, femoral, carotid or brachial artery 12
-Postoperative severe aortic valve regurgitation or stenosis > 30%
-Atrial fibrillation or arrhythmias
-Cerebrovascular accident
-COPD GOLD 3 or 4
-Inability to measure carotid artery blood flow
-Carotid bifurcation anatomically to low
-Contra-indications for femoral arterial catheter placement (e.g., vascular graft)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the accuracy of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement and describe if the limit of agreements are between ±30%.
- Secondary Outcome Measures
Name Time Method To study the trending ability of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement.<br><br>Third Objective: <br>To compare the precision of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement.<br><br>Fourth Objective: <br>To compare the response to therapy (directional changes) of carotid blood flow CO measurement with ultrasound compared to (1) thermodilution CO measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive CO measurement.<br><br>Other Objectives:<br>To study the accuracy of carotid blood flow variation measurement with ultrasound compared to invasive and non-invasive stroke volume variation measurements.