Evaluation and correlation of human salivary biomarker levels before and after application of topical fluoride agents in children with early childhood caries
Not Applicable
- Conditions
- Health Condition 1: K029- Dental caries, unspecified
- Registration Number
- CTRI/2024/08/071874
- Lead Sponsor
- Dr Ganavi G Nayak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Children with 3 to 6 years of age of both the genders
2.Children with DC greater than or equal to 3 in primary teeth , ICDAS II criteria, CODE 02 and 03
3.Parents giving consent for the study.
Exclusion Criteria
1.Children who received fluoride topical application during the last 1 month.
2.Children requiring special health care needs.
3.Pulpally involved and grossly decayed teeth.
4.Children who were on antibiotic therapy within the past 3 months.
5. Children with genetic diseases or syndrome.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluate salivary MMP-8 levels before and after application of MI varnish, 38% SDF and NSF in children with ECC using ELISA. <br/ ><br>Timepoint: Base line <br/ ><br>1 month <br/ ><br>3 months <br/ ><br>
- Secondary Outcome Measures
Name Time Method Correlation & comparision of intragroup & intergroup salivary MMP- 8 levels before & after application of MI varnish, 38% SDF & NSF in children with ECC using ELISATimepoint: Base line <br/ ><br>1 month <br/ ><br>3 months