Supine MRI-guided navigation for tumor localization in breast cancer patients: a feasibility study.
Completed
- Conditions
- Invasive breast cancer1000629110006232
- Registration Number
- NL-OMON43198
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
• Patients with an invasive breast carcinoma, visible on prone CE-MRI.
• Patients who are scheduled for single-seed RSL.
• A signed informed consent.
• Patients >= 18 years old.
Exclusion Criteria
• Contraindication for MRI in supine position or CT.
• Contraindication for gadolinium contrast administration.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome of the study is the accuracy of the supine MRI-guided<br /><br>navigated tumor marker implantation. The accuracy is defined as the difference<br /><br>between planned marker location on supine MRI and actual marker location as<br /><br>seen on CT which is acquired after the implantation procedure. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary outcome of the study is the variability in target volume<br /><br>delineations on pre-operative supine CT with that of registered supine CT-MR<br /><br>scans. The variability is defined as the difference in standard deviation on<br /><br>the surface distance maps between the delineations made on CT only compared to<br /><br>that of registered MR-CT.</p><br>