Intensive Insulin Therapy and Acute Kidney Injury. Analysis Using RIFLE Criteria.

Completed

• Conditions: Kidney; Injury

• Registration Number: NCT00738504
• Lead Sponsor: Hospital Sao Domingos

Brief Summary

The purpose of this study is to determine if intensive insulin therapy really reduces the incidence of acute kidney injury in critically ill patients, using for analysis the RIFLE criteria for definition of AKI.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-06
• Status Verified: 2008-08
• Study First Submitted: 2008-08-18
• Study First Submitted QC: 2008-08-19
• Last Update Submitted: 2008-08-19
• Study First Posted: 2008-08-20
• Last Update Posted: 2008-08-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 337

Inclusion Criteria

• We included 337 adult patients, non pregnant, admitted from July 1, 2004 to December 31, 2006, to a 20-bed multidisciplinary ICU of a general hospital and to an 11-bed trauma center ICU that had at least two blood glucose levels above 150 mg/dl from three measurements obtained in the first 12 hours after admission.

Exclusion Criteria

• pregnant patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the renal function outcome, defined by the RIFLE criteria in patients submitted to two different regimens of glycemic control: a carbohydrate restrictive strategy and intensive insulin therapy.

Trial Locations

Locations (1)

Hospital Sao Domingos; 🇧🇷 Sao Luis, MA, Brazil