Effect of Zinc supplementation on symptoms of migraine
Phase 3
Completed
- Conditions
- migraine.Migraine, unspecified
- Registration Number
- IRCT20121216011763N23
- Lead Sponsor
- Vice chancellor for research, University of Medical Sciences of Esfahan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
aged 20-60 years;
confirmation of migraine by neurologist;
desire to participate in present study;
do not use of oral contraceptive pill,
lack of tension headaches.
Exclusion Criteria
having chronic medical diseases;
use of supplements containing Zn, vitamin E, vitamin C,
Selenium and Beta-carotene
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Migraine symptoms ( severity, frequency and average duration of migraine attacks). Timepoint: At first and end of intervention. Method of measurement: Questionaire.;C-reactive protein (CRP). Timepoint: At first and end of intervention. Method of measurement: Laboratory analysis ( blood test).
- Secondary Outcome Measures
Name Time Method Migraine Disability Assessment. Timepoint: At first and end of intervention. Method of measurement: Questionaire.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie zinc's potential efficacy in migraine pathophysiology?
How does zinc supplementation compare to standard-of-care treatments for migraine management?
Are there specific biomarkers that predict response to zinc in migraine patients?
What adverse events are associated with zinc supplementation in migraine trials?
What combination therapies with zinc show promise in treating refractory migraine?