IRCT20190710044172N1招募中3 期
The effect of zinc supplementation on clinical symptoms, quality of life and its effect on inflammatory biomarkers and the expression of NF-kB, calprotectin, TLR-4 and TNF-a genes in patients with ulcerative colitis
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 50 years（—）
- 性别
- All
入选标准
- •Body mass index 18.5 to 35
- •Diagnosis of ulcerative colitis according to the patient's symptoms, tests and colonoscopy image and intestinal sample pathology
- •Mild to moderate active form of the disease according to the Mayo questionnaire
- •No change in clinical symptoms during the last week of entering the study
- •Absence of concomitant diseases such as malignant diseases and other inflammatory diseases (cancer, kidney failure, heart failure, liver disorders, Wilson's, rheumatoid arthritis, diabetes, psoriasis, Behcet and other inflammatory and autoimmune diseases)
- •No hospitalization and no medication changes during the last 3 months due to the severity of the disease
- •Not having an acute disease (cold, corona and any other viral-bacterial-fungal disease)
- •No intestinal surgery
- •Not taking zinc supplements in the last 2 months
- •Not taking supplements containing antioxidants - omega 3 - vitamin D - probiotic - vitamin E - vitamin A - multivitamin in the last two months
排除标准
- •Use of infliximab, Adalimumab, high dose of corticosteroids (above 40 mg), NSAIDs
- •pregnant and lactating women
- •Taking contraceptives
- •Implementation of special diet such as vegetarian diet, ketogenic diet and gluten-free diet
研究者
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