Zinc supplementation in cirrhotic patients
Not Applicable
- Conditions
- Chronic Liver Failure.Chronic hepatic failure
- Registration Number
- IRCT201106122017N4
- Lead Sponsor
- iver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
age more than 18 years and suffering from cirrhosis.
Exclusion criteria: hepato cellular carcinoma; use of Aldacton or other diuretics over than 50 mg daily; use of anabolic hormones; diuretics or Alb (in recent one month); sever renal or respiratory disorders; pregnancy and lactation; Diabetes mellitus; liver transplantation during the study period and patients with clinical evidence of ascites
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Child-Pugh score. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: Numeral, calculates with severity of Ascitis, total bilirubin, INR, albumin , severity of Encephalopathy.;Serum Zinc level. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: µg/dl.;Copper level. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: µg/dl.;Iron level. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: µg/dl.;Albumin level. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: gr/dl.;BUN. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: mg/dl.;Creatinin. Timepoint: At the first day and the end of 90th day of interventional period. Method of measurement: mg/dl.
- Secondary Outcome Measures
Name Time Method Clinical and lab test. Timepoint: Three month after intervention. Method of measurement: Clinical and laboratory tests.