Ultrasound Imaging of Core Muscles Activity in Multiparous Women With Vaginal Laxity: A Cross-Sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Assessment of transverse abdominis thickness
研究概览
简要总结
This study aims to compare the ultrasound imaging of core muscles activity in multiparous women with vaginal laxity versus normal controls.
详细描述
Vaginal laxity is characterized by the loss of elasticity in the vaginal structure and vaginal looseness, which leads to symptoms including sexual dysfunction, dyspareunia, chronic pelvic pain, and urinary incontinence. It is a symptom of pelvic floor dysfunction. Its mechanisms are not well understood and it is usually worse in women with multiparity.
Since the pelvic floor muscles (PFMs) are one of the core muscles that play a critical role in lumbopelvic stability, their impairment may affect the lumbopelvic area and the activity of other core muscles, like the transverse abdominis, lumbar multifidus, and diaphragm. Therefore, this study aims to compare the ultrasound imaging of core muscles activity in multiparous women with vaginal laxity versus normal controls.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •The participants' age range from 35 to 45 years
- •their body mass index is 25-30 kg/m2,
- •The number of normal deliveries ≤ three times,
- •having a regular menstruation.
- •They participate in the study after at least two years from their last delivery.
排除标准
- •Prior history of disc prolapse and sacroiliac joints, symphysis pubic joint as well as lower limb problems, leg length discrepancy, and diastasis recti.
- •Surgery related to the spine, abdomen or pelvis.
- •Genital prolapse, urinary tract infection, and intrauterine device.
- •Diabetes, chest and/or cardiac disease.
- •Using any drugs for sexual dysfunction.
结局指标
主要结局
Assessment of transverse abdominis thickness
时间窗: 3 months
The measurement of transverse abdominis muscle will be taken from the lower border of internal obliques muscle to the inferior hyperechoic line of peritoneum at rest and during the abdominal drawing in maneuvers (ADIM) for women in both groups, using an ultrasound device.
Assessment of lumbar multifidus thickness
时间窗: 3 months
Lumbar multifidus will be measured, using an ultrasound device, along the line from the L4-5 zygapophyseal joint to the superior border of the lumbar multifidus for women in both groups.
Assessment of pelvic floor muscle force
时间窗: 3 months
It will be assessed, using an ultrasound device, for women in both groups. The position of the bladder base at rest will be marked electronically with an 'X'. The subject will then perform a maximum voluntary pelvic floor muscle contraction and the image will be captured at the moment of maximum displacement. At this time, the subject will relax the pelvic floor muscles. The investigator will then measure the displacement to its current position in the stilled image and will be blinded to the measurement value until after the caliper has been fixed at the end point.
ِAssessment of diaphragmatic force
时间窗: 3 months
Diaphragmatic excursion will be measured, using an ultrasound device, by placing calipers at the bottom and top of the diaphragmatic inspiratory slope. All measurements will be taken at the end of expiration phase for women in both groups.
次要结局
- Short-Form 36 Health Survey (SF-36)(3 months)
- Vaginal Laxity Questionnaire(3 months)
- The Female Sexual Function Index (FSFI)(3 months)
- Modified Oxford grading scale(3 months)
研究者
Doaa A. Osman
Assistant Professor
Cairo University