A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Not Applicable
Not yet recruiting
- Conditions
- Bone Fracture
- Interventions
- Registration Number
- NCT05751304
- Lead Sponsor
- Sohag University
- Brief Summary
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
-The study will include 100 adult patients (18 to 50 years old) with ASA physical status class I and class II undergoing orthopedic lower limb surgeries under itrathecal anathesia .
Exclusion Criteria
- Patient refusal.
- Drug abuse.
- Patient with neurological, psychiatric or neuromuscular disease.
- Chronic pain on medicine.
- Known allergy to the study medications.
- Patients e contraindications to intrathecal anesthesia .
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group D Dexmedetomidine (50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 5μg dexametomidine. Group K Ketamine (50 patients) will receive calculated dose of intrathecal hyperbaric bupivacaine 0.5 % according to body weight and 0.1 mg/kg ketamine.
- Primary Outcome Measures
Name Time Method comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery 1 year comparison between duration of analgesia from Ketamine Vs Dexmedtomidine in the Patients with lower limb surgery.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sohag University Hospital
🇪🇬Sohag, Egypt