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临床试验/NCT01666392
NCT01666392撤回不适用

The Impact of Omega-3 Fatty Acid Supplementation on Markers of Inflammation and Lean Body Mass in Older Adults

University of Memphis2 个研究点 分布在 1 个国家开始时间: 2012年8月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
2
主要终点
C-Reactive protein

研究概览

简要总结

The purpose of this study to determine whether Fish oil (Omega-3 Fatty Acid) supplementation has an impact on inflammation and lean body mass in older adults. The investigators expect that Fish oil supplementation will reduce inflammation and prevent the loss of lean mass compared to placebo.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 60 years of age or over

排除标准

  • Fish, seafood allergies, nut allergies, soy allergies
  • Habitual (>1/week) fish or seafood consumption
  • Current Omega-3 supplement use
  • Gastrointestinal problems
  • Current anti-inflammatory medication use
  • Current anticoagulant medication use

结局指标

主要结局

C-Reactive protein

时间窗: At baseline testing and at 3 month endpoint

Inflammatory marker

IL6

时间窗: At baseline and at 3 month endpoint

Inflammatory cytokine

TNFα

时间窗: At baseline and at 3 month endpoint

Inflammatory cytokine

次要结局

  • Skeletal muscle mass/body composition(At baseline testing and at 3 month endpoint)
  • Lower body muscular strength(At baseline and at 3 month endpoint)
  • Upper body muscular strength(At baseline and at 3 month endpoint)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Zsolt Murlasits

Assistant Professor

University of Memphis

研究点 (2)

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