The effect of omega-3 fatty acid supplementation on oxidative stress in continuous ambulatory peritoneal dialysis patients
Not Applicable
- Conditions
- End Stage Renal Disease.End Stage Renal Disease
- Registration Number
- IRCT201212142417N10
- Lead Sponsor
- Vice Chancellor for Research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1)Clinically stable patients without serious disease.
2)continuous ambulatory peritoneal dialysis (CAPD) for at least 3 months.
3)hypertension stage 1(according to JNC VII) or under treatment.
Exclusion criteria: 1)history of steatorrhea.
2) malignancy.
3) thrombocytopenia (PLT<100000/mm3).
4) abnormal coagulation profile.
5)need for anticoagulation therapy.
6)psychosomatic disorders.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduced gluthation. Timepoint: Begining of the study, after 6 weeks. Method of measurement: ELISA kit, U/mL.;Srum superoxide dismutase. Timepoint: Begining of the study, after 6 weeks. Method of measurement: ELISA kit, U/mL.
- Secondary Outcome Measures
Name Time Method Serum Iron. Timepoint: Begining of the study, after 6 weeks. Method of measurement: ELISA kit, mg/dL.;Serum ferritin. Timepoint: Begining of the study, after 6 weeks. Method of measurement: ELISA kit, mg/dL.;Low density lipoprotein(LDL). Timepoint: Begining of the study, after 6 weeks. Method of measurement: mg/dL.;High density lipoprotein (HDL). Timepoint: Begining of the study, after 6 weeks. Method of measurement: mg/dL.;Triglyceride. Timepoint: Begining of the study, after 6 weeks. Method of measurement: mg/dL.;Cholesterol. Timepoint: Begining of the study, after 6 weeks. Method of measurement: mg/dL.