Brain plasticity and functional recovery in low-functioning stroke patients trained with a dynamic hand orthosis: a MRI pilot study - Brain changes and functional recovery in hand orthosis use

Adelante0 sites5 target enrollmentTBD

Overview

Trial is onging in other countries

Registry

who.int

Start Date

TBD

End Date

December 22, 2016

Last Updated

2 years ago

Study Type

Observational non invasive

Sponsor

Adelante

•Stroke patients:
•Chronic unilateral supratentorial stroke;
•Post\-stroke time \> 12 months;
•Age \>\= 18 years;
•Severely impaired arm\-hand function (AHF): Utrechtse Arm\-hand Test (UAT) score 0\-1;
•Ability to comprehend the test and measurement instructions (in Dutch).;Healthy persons:
•\- age \>\=18 years
•\- no history of stroke
•\- no impaired arm\-hand function
•\- able to comprehend the test and measurement instructions in Dutch.

•CVA patienten:
•Severe cognitive impairments;
•Spasticity in the affected arm\-hand: Modified Ashworth Scale (MAS) score \>\=2;
•Severe additional orthopaedic, rheumatoid, neurologic impairments of the body that may \*further impede arm\-hand task execution;
•No informed consent. ;• MRI contra\-indications: epilepsy, claustrophobia, medication, metal parts in the body (metal plates or screws, clips on blood vessels, braces, metal wire behind teeth, prostheses, piercings, tattoos (including permanent makeup), artificial cardiac valve, anticonception spiral, metal splinters, pacemaker, insulin pump, other electronic devices)