NL-OMON40985
已完成
不适用
Circuit-level mechanisms of cerebral compensation in Parkinson's disease - Cerebral compensation in Parkinson's disease
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- eye movements
- 发起方
- Radboud Universiteit Nijmegen
- 入组人数
- 46
- 状态
- 已完成
- 最后更新
- 2年前
概览
简要总结
Trial is onging in other countries
研究者
入排标准
入选标准
- •A person with Parkinson's disease must meet the following:
- •\- Idiopathic Parkinson\*s disease according to UK brain bank criteria.
- •\- Mild to moderate disease severity (Hoehn and Yahr 1\-3\).
- •\- Dopaminergic therapy with a clear clinical response of non\-tremor symptoms (bradykinesia, rigidity).
- •\- Right\-handed
- •\- Normal/corrected\-to\-normal vision;A control subject must meet the following:
- •\- right handed
- •\- normal / corrected to normal vision
- •\- and be considered healthy
排除标准
- •\- Epilepsy, convulsion or seizure (TMS)
- •\- Serious head trauma or brain surgery
- •\- Large or ferromagnetic metal parts in the head (except for a dental wire)
- •\- Implanted cardiac pacemaker or neurostimulator
- •\- Pregnancy
- •\- Familial epilepsy
- •\- Any other exclusion as per TMS screening form
- •\- Neurological or psychiatric co\-morbidity (e.g. stroke, depression).
- •\- Severe head tremor or dyskinesias
- •\- cognitive impairment (MMSE \< 26\)
结局指标
主要结局
未指定
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