Internal Jugular Ultrasound Measures During Respiration in Children

Completed

• Conditions: Ultrasound Measurements; Normative Values
• Interventions: Device: Sonosite Titan Ultrasound Machine

• Registration Number: NCT02004938
• Lead Sponsor: University of Louisville

Brief Summary

Project Aims: The purpose of this study is to determine the size of the right internal jugular vein (RIJV) in children with normal respiratory physiology during the respiratory cycle and evaluate the reliability of those measurements.

Hypothesis: Ultrasound measurements of internal jugular vein collapse of children can be reliably measured in the respiratory cycle.

Intervention: We will ensure that the patient is not having any respiratory symptoms or signs of dehydration. A clinical asthma score will be assigned using the Modified Woods pulmonary index scoring system. The Gorelick Dehydration Scale with also be calculated.

Using bedside ultrasonography with the Sonosite Titan ultrasound machine, each measurement will be taken with the subject lying in bed with the head of the bed elevated at 45 degrees with the subject's head in the neutral position and then turned 45 degrees leftward. Measurements of the internal jugular vein at maximal inhalation and exhalation will be recorded. Reliability calculations will be assessed.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-08-19
• Study First Submitted QC: 2013-12-03
• Study First Posted: 2013-12-09
• Study Start: 2014-01
• Primary Completion: 2015-01
• Study Completion: 2015-06
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-01
• Last Update Posted: 2017-05-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Subjects ages 6-17 years old presenting to the emergency department (ED) will be enrolled into the normal respiratory function group.

Exclusion Criteria

Children will be excluded from participation if they have: a baseline chronic lung disorder (including asthma), current respiratory illness, fever, Emergency Services Index (ESI) triage category of less than or equal to 2 (emergent acuity), chronic cough, dyspnea with exercise, wheezing, or a history of smoking by self and/or parent report.

Subjects will be excluded if they had prior cardiac/pulmonary disease or surgeries (other than asthma for the acute exacerbation group), significant musculoskeletal abnormalities (such as scoliosis) that might compromise baseline pulmonary function testing, a history of smoking tobacco or marijuana, and prematurity (birth at less than 37 weeks gestation. In addition, those with an allergy to ultrasound gel will be excluded from participation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
normal respiratory function	Sonosite Titan Ultrasound Machine	This will include the 40 subjects enrolled in the study

Primary Outcome Measures

Name	Time	Method
Measurement of diameter of right internal jugular vein during the respiratory cycle at max inhalation and exhalation	During ED stay at initiation of intervention

Secondary Outcome Measures

Name	Time	Method
Clinical Asthma Score	During ED stay at initiation of intervention	Will be recorded using Modified Woods pulmonary index scoring system.
Measurement of level of dehydration	During ED stay	Will measure using the Gorelick scale.

Trial Locations

Locations (1)

Kosair Children's Hospital; 🇺🇸 Louisville, Kentucky, United States