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SDD-SOD-trial.

Completed
Conditions
Patients treated in Intensive Care Units.
Registration Number
NL-OMON26718
Lead Sponsor
participating centers, Dutch SDD Trialists Group
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
3450
Inclusion Criteria

All patients admitted to the ICU with an expected stay> 72 hours in ICU or with an expected duration of mechanical ventilation > 48 hours.

Exclusion Criteria

1. Known allergy to study-medication in patient-history;

2. Pregnancy.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Hospital mortality;<br /><br>2. ICU-mortality.
Secondary Outcome Measures
NameTimeMethod
1. Prevalence of antibiotic resistance;<br /><br>2. Duration of mechanical ventilation;<br /><br>3. Duration of ICU-stay;<br /><br>4. Incidence of hospital infections;<br /><br>5. Antibiotic use;<br /><br>6. Health care costs.
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