Selective Digestive Decontamination (SDD) - Selective Orophayngeal Decontamination (SOD) trial

Completed

• Conditions: Infection in ICU patients; Infections and Infestations

• Registration Number: ISRCTN35176830
• Lead Sponsor: niversity Medical Centre Utrecht (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-12-20
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3450

Inclusion Criteria

All patients admitted to the ICU with an expected stay> 72 hours in ICU or with an expected duration of mechanical ventilation > 48 hours

Exclusion Criteria

1. Known allergy to study-medication in patient-history
2. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Hospital mortality<br>2. ICU-mortality

Secondary Outcome Measures

Name	Time	Method
1. Prevalence of antibiotic resistance<br>2. Duration of mechanical ventilation,<br>3. Duration of ICU-stay,<br>4. Incidence of hospital infections,<br>5. Antibiotic use,<br>6. Health care costs.