Skip to main content
Clinical Trials/NCT01025960
NCT01025960
Completed
Not Applicable

Comparison of Detection of Polyps During Both Insertion and Withdrawal Phases of Colonoscopy Versus the Standard Practice of Detection of Polyps During the Withdrawal Phase of Colonoscopy: A Prospective Quality Improvement Study

The Cleveland Clinic1 site in 1 country768 target enrollmentNovember 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Cancer
Sponsor
The Cleveland Clinic
Enrollment
768
Locations
1
Primary Endpoint
Adenoma detection rates for each method
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

Colorectal cancer (CRC) is the third most common cancer and second leading cause of cancer deaths in western countries. Colonoscopy is a preferred colorectal screening modality since it has both diagnostic and therapeutic capability. Detection and removal of polyps at colonoscopy decreases the incidence and mortality from colorectal cancer.

Typical practice is to insert the colonoscope rapidly until it reaches the cecum (a pouch-like portion of the intestines, where the large bowel and the small bowel meet). The physician then withdraws the colonoscope slowly and looks for any polyps or abnormalities within the large bowel. The purpose of this study is to compare this standard practice to the approach whereby the physician examines the bowel as the scope is initially inserted AND as the colonoscope is withdrawn from patients' colons.

Registry
clinicaltrials.gov
Start Date
November 2009
End Date
January 2012
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patients
  • Patients able to provide an informed consent
  • Patients undergoing colonoscopy

Exclusion Criteria

  • Pregnant women
  • Patients with Familial Adenomatous Polyposis Syndromes (FAP)
  • Patients with Hereditary Non-polyposis Colon Cancer Syndrome (HNPCC)
  • Patients who have undergone previous surgical resection of the colon
  • Patients who have been diagnosed with inflammatory bowel disease

Outcomes

Primary Outcomes

Adenoma detection rates for each method

Time Frame: within the first 30 days after colonoscopy

Secondary Outcomes

  • Comparison of procedure times for each method(1 year)
  • Percentage of patients with at least one adenoma detected by each method(1 year)
  • Comparison of percentage of adenomas classified as high risk for each method(1 year)

Study Sites (1)

Loading locations...

Similar Trials