Effect of Moisturizer on Malaysian Women Facial Skin

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT05657379
• Lead Sponsor: Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre

Brief Summary

The goal of this clinical trial is to evaluate the effect of Product X on facial skin of middle-aged women in Malaysia. The main questions it aims to answer are:

1. The effect of Product X on skin hydration of middle-aged women in Malaysia.

2. The effect of Product X on skin elasticity of middle-aged women in Malaysia.

3. The effect of Product X on skin wrinkle of middle-aged women in Malaysia.

4. To observe any adverse effect occurrence with the use of Product X.

Participants will used Product X for 8 week and the skin assessment will be carried out at baseline, week 2, 4 and week 8.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-15
• Study First Submitted: 2022-12-07
• Study First Submitted QC: 2022-12-16
• Study First Posted: 2022-12-20
• Primary Completion: 2023-09-30
• Study Completion: 2023-09-30
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-27
• Last Update Posted: 2023-11-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Malaysian citizen
• Middle-aged woman (40-60 years old)

Exclusion Criteria

• Participants taking isotretinoin
• Immunocompromised patients or participants with any skin diseases or diseases that may compromised the participants well-being and study outcome.
• Participant who undergo any cosmetic procedures such as laser & light treatment for the past three months.
• Participant with a history of facial surgery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change in skin elasticity from baseline and at week 2, 4 and 8 after using Product X	Baseline, week 2, 4 and 8	Skin elasticity will be assessed using JANUS III skin analyzer
Adverse effect after using Product X	Week 8	Based on adverse effect occurrence on participants that occur during study period (8 weeks)
Change in skin hydration from baseline and at week 2, 4 and 8 after using Product X	Baseline, week 2, 4 and 8	Skin hydration will be assessed using JANUS III skin analyzer
Change in skin wrinkles from baseline and at week 2, 4 and 8 after using Product X	Baseline, week 2, 4 and 8	Skin wrinkles will be assessed using JANUS III skin analyzer and Wrinkle Severity Rating Scale (WSRS). For WSRS, dermatologists will evaluate participants' wrinkles based on 5-point photonumeric rating scale that will objectively evaluate the severity of crow's feet at rest (static) and with a smiling expression (dynamic). The scale scores are 0 for no wrinkles, 1 for very fine wrinkles, 2 for fine wrinkles, 3 for moderate wrinkles, and 4 for severe wrinkles.

Trial Locations

Locations (1)

Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre; 🇲🇾 Petaling Jaya, Selangor, Malaysia