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Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia

Not Applicable
Completed
Conditions
Schizophrenia
Interventions
Device: eldith DC-stimulator (Neuroconn, Ilmenau, Germany)
Registration Number
NCT01378078
Lead Sponsor
Ludwig-Maximilians - University of Munich
Brief Summary

Transcranial direct current stimulation (tDCS) showed beneficial effects on cognition in healthy subjects and depressed patients. In this study, patients with treatment resistant negative syndrome in schizophrenia will be treated with direct current stimulation. fMRI measures will be performed.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • schizophrenic patients with a negative syndrome. PANSS > 40.
Exclusion Criteria
  • other psychiatric or neurologic diseases.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
shameldith DC-stimulator (Neuroconn, Ilmenau, Germany)patients receive sham tDCS stimulation
activeeldith DC-stimulator (Neuroconn, Ilmenau, Germany)active transcranial direct current stimulation
Primary Outcome Measures
NameTimeMethod
SANS reduction4 weeks after baseline

decrease by 30%

Secondary Outcome Measures
NameTimeMethod
neuropsychological tests4 weeks after baseline

increase in SOPT by 30% increase in TMT by 30%

Trial Locations

Locations (1)

Klinik fuer Psychiatrie

🇩🇪

Munich, Germany

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