The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults

Not Applicable

Completed

• Conditions: Healthy; Cognitive Symptom
• Interventions: Other: Transcranial Direct Current Stimulation

• Registration Number: NCT04873804
• Lead Sponsor: Medipol University

Brief Summary

Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.

Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.

Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-10
• Primary Completion: 2020-05-10
• Study Completion: 2020-06-10
• Study First Submitted: 2021-04-14
• Status Verified: 2021-05
• Study First Submitted QC: 2021-05-04
• Last Update Submitted: 2021-05-04
• Study First Posted: 2021-05-05
• Last Update Posted: 2021-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

• being 18-30 years old

Exclusion Criteria

• alcohol and substance addiction
• previous mental illness
• having mental and cognitive problems
• a history of head trauma
• having cardiovascular disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
LEFT DLPFC	Transcranial Direct Current Stimulation	The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder.
RİGHT PPC	Transcranial Direct Current Stimulation	The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder.
Sham	Transcranial Direct Current Stimulation	Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current.

Primary Outcome Measures

Name	Time	Method
Neuropsychiatric Test Battery	3 weeks	It is a test battery for getting detailed information about general cognitive status.
Beck Depression Scale	3 weeks	It measures the symptoms seen in depression such as emotional, cognitive and motivational. It includes 21 items determine a behavioral feature related to depression. Items are numbered from 0 to 3. The goal is to objectively break down the degree of symptoms.; The total score of all answers is calculated as follows: 0 to 9 points: Minimally depressive symptoms 10 to 16 points: Mild depressive symptoms Between 17 and 29 points: Moderate depressive symptoms Between 30 and 63 points: Severe depressive symptoms

Trial Locations

Locations (2)

Medipol Mega Hospital; 🇹🇷 Istanbul, Turkey

Damla Ören; 🇹🇷 Istanbul, Turkey