Comparing the effect of Narrowband ultraviolet B (UVB) therapy to therapy with natural sunlight and an amino acid lecithin cream on dermatologic symptoms

Not Applicable

Completed

• Conditions: Psoriasis; Atopic dermatitis; Pruritus; Vitiligo; Skin - Dermatological conditions

• Registration Number: ACTRN12620000546954
• Lead Sponsor: DR ROWLAND NOAKES

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-07
• Study Completion: 2023-03-11
• Last Update Posted: 20 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Adult patients with psoriasis, atopic dermatitis, pruritus or vitiligo eligible for treatment with Narrowband UVB

Exclusion Criteria

Patients under the age of 18
Pregnant or lactating females
Patients with known sensitivity to the topical agents
Patients with cutaneous T or B cell lymphoma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of patients with a meaningful clinical response defined as an improvement of 75% in the baseline PASI score for participants with psoriasis, EASI score for participants with atopic dermatitis, VASI score for participants with vitiligo or visual analogue scale for participants with pruritus<br>[12 weeks for psoriasis, atopic dermatitis and pruritus<br>6 months for vitiligo];A skin biopsy from a light protected and light exposed area will also be taken for immuno-histochemical staining to ascertain cytochrome P450 induction[12 weeks for psoriasis, atopic dermatitis and pruritus. 24 weeks for vitiligo]

Secondary Outcome Measures

Name	Time	Method
nil[Not applicable]