Comparing the effect of albumin and crystalloid serum as resuscitation fluid in survival of patients with severe sepsis shock

Vice chancellor for research, Tabriz University Of Medical Sciences.0 个研究点目标入组 20 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•age between 12 to 75 years old; existence of at least two symptoms of SIRS syndrome (body temperature above 38 or below 36 ° C.; respiratory rate above 20 or PCO2 less than 32 or need for mechanical ventilation; heart rate more than 90, leukocytosis above 12,000 or leukopenia less than 4000 or band cells in peripheral blood smear); existence of a focal infection based on positive culture or existence of an obvious infected area such as peritonitis or pneumonia; need to resuscitation with fluid (tachycardia; systolic blood pressure less than 100 mm Hg or mean arterial pressure less than 75 mm Hg; urine volume less than 0.5 cc/kg/hr; need for vasopressor to maintain blood pressure; central venous pressure (CVP) less than 10 mm Hg).
•Exclusion criteria: brain death patients; patients undergoing plasmapheresis; contraindications of albumin infusion; heart failure or pulmonary failure or renal failure; transplant patients; patients with burns; heart surgery at 3 recent months.

发起方

Vice chancellor for research, Tabriz University Of Medical Sciences.