A comparison of the effect of receiving albumin in the initial 8 to 12 hours and after 24 hours after burn on the incidence of fluid creep in severe burn patients

Rasht University of Medical Sciences0 sites96 target enrollmentStarted: TBDLast updated: August 30, 2021

Trial Snapshot

No summary available.

•burn patients with 2nd and 3rd degree burn area more than 20 percent TBSA
•full-thickness burn area more than 10 percent TBSA
•patients needing vasopressor usage in the first 24 hours of admission
•patients needing intubation and mechanical ventilation in the first 24 hours of admission

•patients not needing albumin infusion according to the clinical decision of specialist
•critically ill patients with expected death in first 24 hours or patients that expired in first 24 hours of admission
•brain death in first 24 hours
•patients admitted more than 8 hours after burn
•patients with chronic underlying diseases affecting serum albumin level, including nephrotic syndrome, cirrhosis, malnutrition, exudative enteropathy
•a history of cardiac surgery or myocardial infarction in recent 5 years
•patients with high-voltage electrical burn injuries
•patient does not accept entering the study
•patients receiving plasmaphresis
•a history of reaction to human albumin

Sponsor

Rasht University of Medical Sciences