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Dose Linearity Study of Codeine Sulfate Under Fasted Conditions

Phase 1
Completed
Conditions
Pain
Registration Number
NCT01009697
Lead Sponsor
Roxane Laboratories
Brief Summary

The objective of this study was to examine the dose linearity of Roxane Laboratories' 15 mg, 30 mg, and 60 mg codeine sulfate tablets under fasted conditions

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
34
Inclusion Criteria
  • No clinically significant abnormal findings on the physical examination, medical history, or clinical laboratory results during screening.
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Exclusion Criteria
  • Positive test for HIV, Hepatitis B, or Hepatitis C.
  • Treatment with known enzyme altering drugs.
  • History of allergic or adverse response to Codeine Sulfate or any comparable or similar product.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
bioequivalence determined by statistical comparison Cmax21 Days
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CEDRA Clinical Research

🇺🇸

Austin, Texas, United States

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