Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies: a Prospective Cohort
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Mullerian Anomaly of Uterus, Nec
- Sponsor
- University Hospital, Ghent
- Enrollment
- 1500
- Locations
- 1
- Primary Endpoint
- Fertility
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian anomalies.
Detailed Description
Mullerian anomalies are rare, therefore they are not well known and not often considered as differential diagnosis. This causes a delay in the diagnosis with risk of long lasting symptoms and adverse effects on the reproductive function. However, the diagnosis can be made more accurately with improved diagnostic tools. Moreover, minimally invasive surgery allows for preservation and potential improvement of fertility in these women. The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian anomalies.
Investigators
Eligibility Criteria
Inclusion Criteria
- •women with a uterus
- •presence of a mullerian variation
- •Maximum age 45y
Exclusion Criteria
- •women without a uterus
- •aged \>45y
Outcomes
Primary Outcomes
Fertility
Time Frame: 18 weeks after conception
Early pregnancy loss
Surgical success
Time Frame: 15 years after surgery
Relief of symptoms after surgery
Surgical approach
Time Frame: During surgery
Different surgical approaches used
Secondary Outcomes
- Diagnostic accuracy(at the time of diagnostic workup)
- Obstetric complications(1 year after conception)