Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies: a Prospective Cohort
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- Fertility
研究概览
简要总结
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian anomalies.
详细描述
Mullerian anomalies are rare, therefore they are not well known and not often considered as differential diagnosis. This causes a delay in the diagnosis with risk of long lasting symptoms and adverse effects on the reproductive function. However, the diagnosis can be made more accurately with improved diagnostic tools. Moreover, minimally invasive surgery allows for preservation and potential improvement of fertility in these women.
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian anomalies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 45 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women with a uterus
- •presence of a mullerian variation
- •Maximum age 45y
排除标准
- •women without a uterus
- •aged >45y
研究组 & 干预措施
patients with a mullerian variation
结局指标
主要结局
Fertility
时间窗: 18 weeks after conception
Early pregnancy loss
Fertility
时间窗: 10 years after trying to conceive
Time to clinical pregnancy
Surgical success
时间窗: 15 years after surgery
Relief of symptoms after surgery
Surgical approach
时间窗: During surgery
Different surgical approaches used
次要结局
- Diagnostic accuracy(at the time of diagnostic workup)
- Obstetric complications(1 year after conception)