Can Caffeine prevent the cessation of breathing in preterm newborn babies?

Phase 4

• Conditions: Prematurity; Apnea of Prematurity; Low Birth Weight; Reproductive Health and Childbirth - Complications of newborn; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12621001000897
• Lead Sponsor: Mansoor Aslamzai

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-07-30
• Last Update Posted: 10 August 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

Neonates with the following criteria:
1. The gestational age of 34 weeks or less.
2. The birth weight less than 1500g.

Exclusion Criteria

Neonates with the following conditions:
1. Neonatal Meningitis diagnosed by CSF and complete blood count.
2. Neonatal Pneumonia diagnosed by infiltration on chest x-ray and complete blood count.
3. Visible CNS malformation.
4. Cyanotic Congenital Heart Diseases detected by echocardiography.
5. Hypoxic-ischemic encephalopathy detected by Levene or Sarnat-Sartant Scoring System.
6. Severe perinatal asphyxia diagnosed as an Apgar score less than 4.
7. Hypoglycemia or blood glucose level less than 40mg/dl.
8. Hypocalcemia or blood calcium level less than 7.5mg/dl.
9. Severe Anemia defined as hemoglobin less than 10g/dl
10. Intraventricular hemorrhage detected by ultrasonography.
11. Hyponatremia or serum sodium level less than 135mq/l
12. Hypernatremia or serum sodium level more than 145mq/l
13. Parents who declined the consents.

Study & Design

• Study Type: Interventional
• Study Design: Not specified