Testing the feasibility of nicotine-assisted reduction to stop in pharmacies: a 2x2 factorial trial

niversity of Birmingham (UK)0 个研究点目标入组 320 人开始时间: 2010年3月18日最近更新: 2017年3月13日

试验速览

暂无简介。

•1. Male or female, 18 years or older
•2. Smokes at least 10 cigarettes or 12.5g of loose tobacco daily as roll your own cigarettes, or blows 15ppm or above on CO recording
•3. Do not intend to stop in the next month, but are prepared to reduce their consumption with any of the programmes offered
•4. Evidence of a personally signed and dated informed consent document indicating that the subject has been informed of all pertinent aspects of the study and consents to participate and be randomised to either arm and have either a telephone or email for follow-up

•1. Currently using other NRT, bupropion, nortriptyline, mecamylamine, reserpine, or varenicline, or undergoing any treatment for tobacco dependence (e.g. acupuncture),
•2. Unstable angina pectoris, myocardial infarction, or cerebrovascular accident during the last 3 weeks,
•3. Severe cardiac arrhythmia
•4. Currently uncontrolled hyperthyroidism
•5. Active phaeocromocytoma
•6. Pregnancy, lactation or intended pregnancy
•7. Participation in other medicinal trials within the last three months and during study participation,
•8. Previously had severe skin reactions to nicotine patches or severe eczema or other skin diseases that make patch use hazardous or undesirable
•9. Severe acute or chronic medical or psychiatric condition or previously diagnosed clinically important renal or hepatic disease, that may increase the risk associated with study participation or may interfere with the interpretation of study results and, in the judgment of the investigator, would make the subject inappropriate for entry into this study

发起方

niversity of Birmingham (UK)