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Clinical Trials/NCT00888979
NCT00888979
Completed
Not Applicable

Pilot Study of Nicotine Replacement for Smoking Cessation During Pregnancy

Hartford Hospital1 site in 1 country10 target enrollmentApril 2009

Overview

Phase
Not Applicable
Intervention
Nicotrol Inhaler
Conditions
Tobacco Use Disorder
Sponsor
Hartford Hospital
Enrollment
10
Locations
1
Primary Endpoint
Number of Days of Inhaler Use
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

We plan to examine the feasibility, acceptability, preliminary quit rates, overall nicotine exposure and adverse effects of the nicotine inhaler for smoking cessation in pregnancy.

Detailed Description

Subjects in this pilot study are healthy pregnant women who wish to quit smoking. They will set a quit date and use the nicotine inhaler for 4 weeks. They will receive behavioral counseling in addition to the inhaler for 4 weeks.

Registry
clinicaltrials.gov
Start Date
April 2009
End Date
April 2014
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 13-26 weeks pregnant
  • Smoking at least 5 cigarettes per day the preceding 7 days
  • Motivated to quit smoking (at least 7 on a 10 pt. scale)
  • Able to speak English
  • Intend to carry pregnancy to term
  • Stable residence

Exclusion Criteria

  • Current drug or alcohol abuse or dependence (other than methadone maintenance
  • Twins or multiple gestation
  • Unstable psychiatric disorder
  • Unstable medical problems
  • Known congenital abnormality
  • High risk pregnancy

Arms & Interventions

Nicotrol with Behavioral Counseling

Nicotrol Inhaler: 10 mg of nicotine per one inhaler cartridge. Inhaler use will substitute the usual smoking pattern

Intervention: Nicotrol Inhaler

Outcomes

Primary Outcomes

Number of Days of Inhaler Use

Time Frame: Baseline to 4 weeks

Secondary Outcomes

  • Cartridge Use(Baseline to 4 weeks)
  • Change in Number of Cigarettes Used Per Day From Baseline to 4 Weeks.(Baseline to 4 weeks)

Study Sites (1)

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