Objective Visual Quality Analysis System is Used in Cataract

• Conditions: Cataract
• Interventions: Other: Observational research, not applicable

• Registration Number: NCT04757350
• Lead Sponsor: Wuhan Union Hospital, China

Brief Summary

The Objective Visual Quality Analysis System (OQAS) is a new inspection technology used to objectively assess the visual quality of the human eye. The investigators use this advanced technology to evaluate and follow up cataract patients before and after surgery, and observe the incidence, severity, and treatment effects of postoperative complications such as postoperative complications, and analyze the severity and artificial The influence of lens type, postoperative time, systemic diseases and other factors on the effect of cataract surgery, in order to discover the key factors that affect the effect of cataract surgery and the management of complications, and provide a useful reference for improving the level of cataract prevention and treatment in China

Detailed Description

The Objective Visual Quality Analysis System (OQAS) is a new inspection technology used to objectively assess the visual quality of the human eye. It can detect the impact of ocular refractive system diseases on the objective visual quality of patients. It is currently mainly used to assess the progress of cataracts and help selection the timing of surgery has achieved good clinical results. Before the emergence of OQAS, the rating of cataracts largely relied on the subjective experience of physicians, and OQAS could accurately assess the effects of cataracts on the visual quality of the human eye by quantitatively detecting the light scattering index (OSI) of the refractive medium of the human eye. The impact provides a quantitative evaluation basis for the diagnosis and treatment of cataract and research. However, the application of OQAS in cataract surgery effect evaluation and postoperative complications management is still lacking. After cataract surgery, although the cloudy lens nucleus and cortex have been removed, the original refractive error, vitreous opacity, postoperative posterior capsule folds, posterior dysfunction and many other factors may still affect the objective of the human eye visual quality, and ordinary visual inspection is difficult to find this effect . In addition, preoperative OSI and other indicators of cataract, as an exposure factor, may affect the incidence of postoperative complications, such as after-cataract, macular edema, etc. It is worthy of further study. The application of OQAS can accurately assess the improvement of objective visual quality after cataract surgery, and find and remove other factors that affect OSI. In addition, for one of the most common complications after cataract surgery-after-onset disorder, there is no uniform rating standard in the academic circles, and OQAS can provide objective data for the rating of after-onset disorder, so as to provide information on the postoperative complications such as late-onset disorder. Provide reference for the management of . The research team intends to use OQAS to evaluate and follow up cataract patients before and after surgery, and observe the incidence, severity, and treatment effects of postoperative complications such as after-cataract, analyze the severity of cataract or after-cataract, and intraocular lens The influence of factors such as type, postoperative time, systemic disease on the effect of cataract surgery. We will also rate the posterior disorder based on OSI, and examine the effects and risks of different grades of posterior disorder after laser capsulotomy and other treatments, in order to use OQAS to better guide cataract surgery and postoperative complications management.

Study Timeline

• Status Verified: 2021-02
• Study Start: 2021-02-01
• Study First Submitted: 2021-02-09
• Study First Submitted QC: 2021-02-13
• Last Update Submitted: 2021-02-13
• Study First Posted: 2021-02-17
• Last Update Posted: 2021-02-17
• Primary Completion: 2022-01-01
• Study Completion: 2022-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Cataract patients aged 18-90 or patients after cataract surgery；
2. Signed and dated informed consent；
3. Commit to abide by the research procedures and cooperate with the implementation of the whole process research

Exclusion Criteria

1. Obvious conjunctivitis；
2. Obvious corneal epithelial punctate staining, corneal epithelial shedding；
3. Keratitis；
4. Uveitis；
5. Corneal scar；
6. Severe vitreous opacity or hemorrhage；
7. Other situations deemed unsuitable for inclusion in this study after evaluation by ophthalmologists.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cataract	Observational research, not applicable	Research subjects should meet the following criteria: Signed and dated informed consent form Commitment to abide by the research procedures and cooperate with the implementation of the whole process of research 18-90-year-old cataract patients or patients after cataract surgery

Primary Outcome Measures

Name	Time	Method
Change from Contrast Sensitivity at 6 months	6 months	CS after cataract surgery 1 week、1month、3month、6month
Change from visual acuity at 6 months	6 months	VA after cataract surgery 1 week、1month、3month、6month
Change from Objective Scatter Index at 6 months	6 months	OSI after cataract surgery 1 week、1month、3month、6month
Change from Patient Satisfaction Scale at 6 months	6 months	Patient Satisfaction Scale after cataract surgery 1 week、1month、3month、6month.The minimum values is 0 and maximum values is 100.100 points mean the best outcome.

Trial Locations

Locations (1)

Union Hospital; 🇨🇳 Wuhan, Hubei, China