High HDL cholesterol and ASCVD risk score
- Conditions
- Health Condition 1: E789- Disorder of lipoprotein metabolism, unspecifiedHealth Condition 2: E789- Disorder of lipoprotein metabolism, unspecified
- Registration Number
- CTRI/2019/12/022320
- Lead Sponsor
- Kasturba Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients in the age-group 18.00 years -75 years of both sexes and who are willing to give consent will be included.
High HDL cholesterol will be taken as >50mg/dl in male, > 60mg/dl in females
Age and sex matched controls with normal HDL cholesterol will be taken
Patient on high intensity exercise
Cholesterol lowering diet
Uncontrolled diabetes mellitus ( FBS > 200mg/dl, PPBS > 250mg/dl, HbA1C >8%- any
one)
Hypothyroidism (TSH >10 )
• Major organ dysfunction including liver and kidney ( including nephrotic syndrome)
Sepsis
Clinical evidence of Malignancy
Steroid usage, OCPs and hormonal supplements
High risk groups ( pregnant, retro positive patients)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) We will know if high HDL cholesterol is beneficial in terms of decreasing ASCVD risk score. <br/ ><br>2) Know the lifestyle of the subjects with high HDL cholesterol and its benefits <br/ ><br>Timepoint: 2 years
- Secondary Outcome Measures
Name Time Method To find out populations with CETP deficiency and their ASCVD riskTimepoint: 2 years