NCT02178839Unknown不适用
The Effect of Oral β- Glucan Supplement on Anthropometric Measurements, Appetite, Insulin Resistance, Liver Echogenicity and Enzymes in Non Alcoholic Fatty Liver Disease Treating With Hypocaloric Diet and Vitamin E
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Liver Echogenicity
研究概览
简要总结
The Objective of This Study is Evaluating the Effect of oral β- glucan Supplement on Anthropometric Measurements, Appetite, Insulin Resistance, Liver echogenicity and Enzymes in Non Alcoholic Fatty Liver Patients Treating with Hypocaloric Diet and Vitamin E.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Non Alcoholic Fatty Liver Disease From Both Sex
- •Age 18-55 years
- •BMI more than 25 Kg/m2
排除标准
- •Alcohol Consumption
- •Pregnancy or lactation or menopause
- •Being a professional athlete
- •A history of cancer
- •Risk of high blood pressure (in the case of drug use)
- •Heart disease - cardiovascular, pulmonary, renal and diabetes
- •Liver transplantation and other chronic or acute Liver diseases such as hepatitis B, C and liver infections
- •The History of inherited disorders affecting the liver
- •A history of autoimmune disease
- •History of food allergies
- •Taking certain medications such as blood pressure control, statins, insulin sensitivity enhancers and hepatotoxic drugs
结局指标
主要结局
Liver Echogenicity
时间窗: 8 weeks
Liver Echogenicity Describes by Grade,
Liver Enzymes
时间窗: 8 weeks
Enzymes ALP (Alkanin Phosphatase), ALT (Alanin Amino Transferase) and AST (Aspartat Amino Transferase)
次要结局
- Anthropometric Measurement WHtR(4 weeks, 8 weeks)
- Appetite(4 weeks, 8 weeks)
- Insulin Resistance(8 weeeks)
- Anthropometric Measurement WC(4weeks, 8 weeks)
- Anthropometric Measurement WHR(4 weeks, 8 weeks)
- Anthropometric Measurement BMI(4 weeks, 8 weeks)
- Peptide YY (PYY) Hormone(8 weeks)
- Cholecystokinin (CKK) Hormone(8 weeks)
- Fasting Blood Sugar(8 weeks)
研究者
研究点 (1)
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