Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI): an Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes
研究概览
简要总结
The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.
详细描述
Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-75 years
- •Suspension laryngoscopy for diagnostic or therapeutic purposes
- •Total intravenous anesthesia using propofol and remifentanil
排除标准
- •age <18 yrs or >75 yrs
- •arrythmia
- •administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
- •psychiatric diseases
- •autonomic nervous system disorders (epilepsy)
结局指标
主要结局
Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes
时间窗: Before induction of anesthesia, 1 min after beginning of procedure, at steady-state anesthesia during procedure (an expected average of 10 min) and at arousal from general anesthesia in the end of procedure (an expected average of 20 min)
次要结局
未报告次要终点
研究者
Emmanuel Boselli
MD, PhD
Hôpital Edouard Herriot