Prediction of Immediate Postoperative Pain Using Analgesia/Nociception Index (ANI): an Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Emmanuel Boselli
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Analgesia/Nociception Index (ANI) receiver operating characteristic (ROC) curve area under the curve (AUC) for the prediction of immediate postoperative pain
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The aim of this study is to evaluate the performance of Analgesia/Nociception Index (ANI) measured at the end of surgery for the prediction of immediate postoperative pain in postoperative care unit in adult patients undergoing general anesthesia.
Detailed Description
Assessment of the performance of ANI to predict immediate postoperative pain on a 0-10 numerical rating scale (NRS) \>3 by building a receiver operating characteristic curve.
Investigators
Emmanuel Boselli
MD, PhD
Hôpital Edouard Herriot
Eligibility Criteria
Inclusion Criteria
- •ear-nose-throat or orthopedic surgical procedures
- •halogenated and remifentanil-based general anesthesia
Exclusion Criteria
- •age \<18 yrs or \>75 yrs
- •arrythmia
- •administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
- •psychiatric diseases
- •autonomic nervous system disorders (epilepsy)
- •inability to understand the verbal rating pain scale
Outcomes
Primary Outcomes
Analgesia/Nociception Index (ANI) receiver operating characteristic (ROC) curve area under the curve (AUC) for the prediction of immediate postoperative pain
Time Frame: At day 0 at the end of surgery immediately before extubation for ANI and at arrival in postoperative care unit within 10 minutes after arrival
ROC curve AUC