The prospective pilot trial for evaluating the effects of probiotics on the clinical course of the HIV-1-infected children on ART and ART naive at National Hospital of Pediatrics in Hanoi, Vietnam
Not Applicable
- Conditions
- Human immunodeficiency virus type 1 (HIV-1) infection
- Registration Number
- JPRN-UMIN000015044
- Lead Sponsor
- Graduate school of Medical Sciences, Kanazawa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
- Intervention group 1 and 2: (1) whose status are Acquired immune deficiency syndrome, AIDS (2) who have symptoms of intestinal infection. (3) who have had any treatment which might influence on her/his immune system within last eight weeks of starting to take test substance. (4) who are allergic to milk - Intervention group 3: (1) who have symptoms of intestinal infection. (2) who have had any treatment which might influence on her/his immune system within last eight weeks of starting to take test substance. (3) who are allergic to milk
Study & Design
- Study Type
- Interventional,observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The concentration of the plasma 16SrDNA/RNA before and after the ingestion of LCS
- Secondary Outcome Measures
Name Time Method - The concentration of the plasma soluble CD14 - The plasma HIV load - The plasma CD4 count - The concentration of the plasma cytokines - The profile of the CD25/CD4 ratio on PBMC