The Effect of Sucrose on Pain Relief During Venous Blood Sampling in Preterm Infants: a Comparison of Two Different Doses

Norwegian University of Science and Technology2 sites in 2 countries50 target enrollmentJanuary 2015

ConditionsPain

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Pain
Sponsor: Norwegian University of Science and Technology
Enrollment: 50
Locations: 2
Primary Endpoint: pain
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Despite the fact that oral sucrose is the most frequently studied non-pharmacological intervention for procedural pain relief in infants, there is a paucity of data on the minimal effective dose. The aim of this study is to find the minimal effective dose of sucrose to reduce pain during a single venous blood sampling procedure.

Registry

clinicaltrials.gov

Start Date

January 2015

End Date

June 2016

Last Updated

5 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Norwegian University of Science and Technology

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•born preterm
•more than 1000 gram

Exclusion Criteria

•severe intraventricular hemorrhage
•cerebral malformations
•other malformations requiring surgery
•medication that may impair pain expression (opioids, paracetamol, sedatives)

Outcomes

Primary Outcomes

pain

Time Frame: 1 week

assessed by Premature Infant Pain Profile-Revised (PIPP-R). Pain score related to the blood sampling will be performed two times: at skin puncture and immediately after the needle has been removed