Effect of fluvoxamine in pruritus in hemodialysis patients
Not Applicable
- Conditions
- Hemodialysis.N18.5
- Registration Number
- IRCT2012111211438N1
- Lead Sponsor
- Arak University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 53
Inclusion Criteria
Inclusion criteria;hemodialysis patients; filling the testimonial questionnaire;age 20-70 years;thrice weekly hemodialysis;KT/V>0.9(keeping the optimum adequecy of dialysis)
exclusion criteria:dermatitis disease;B and C hepatitis;cholestasis and other liver disease;treatment with corticosteroid in recent months;anemia(Hb<10);treatment with other SSRI;TCA;MAOI;5-HT3 receptor antagonist ;phenothiazine;lithium;history of seizure;pregnancy and breastfeeding;hypomania;consumption of theophylinand warfarin;sever chronic nausea;hyponatremia
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pruritus score. Timepoint: before intervention;8 weeks after intervention;20 weeks after intervention. Method of measurement: 5-D questionnaire.
- Secondary Outcome Measures
Name Time Method Fluvoxamine. Timepoint: weekly. Method of measurement: milligram.;Placebo. Timepoint: weekly. Method of measurement: milligram.;Side effects. Timepoint: weekly. Method of measurement: quallitative.