The Influence of Dimensional Anatomic Variables on the Outcomes of Maxillary Sinus Grafting Procedures
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Histomorphometric proportion of vital bone
研究概览
简要总结
The hypothesis of this study is that there is a significant difference in bone maturation after sinus grafting determined by the distance from the buccal to the palatal wall of this cavity.
详细描述
Inadequate alveolar bone height as a consequence of tooth loss is a common limitation for properly placing endosseous dental implants in the posterior maxilla. Grafting of the maxillary sinus has been regarded as one of the most reliable surgical alternatives to correct this problem. Several sinus grafting techniques, using different materials, have been reported showing high survival rates. However, there are many factors that may alter the outcomes of this procedure.
The maturation and consolidation of the grafted area relies on the proper formation of a functional graft-vital bone complex. This maturation process requires an adequate migration of osteogenic cells from native bone, that could be limited in situations where the dimensions of the maxillary sinus are excessive. Hence, the purpose of this research project is to determine the influence of the distance from the lateral to the medial wall of the maxillary sinus on the outcomes of a sinus augmentation procedures performed using the lateral approach using clinical, radiographic and histomorphometric analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults patients (Older than 18 years), up to 85 years-old.
- •Physical status according to the American Society of Anesthesiologists (ASA) I or II
- •Patient in need of a sinus grafting using the lateral approach to allow the proper placement of dental implants. The remaining bone height must be 3 mm or less.
- •No uncontrolled systemic disease or condition known to alter bone metabolism
- •Adequate oral hygiene (O'Leary plaque score ≤20%)
排除标准
- •Long term (>2 weeks) use of antibiotics in the past 3 months
- •Patients smoking more than half-pack a day
- •Patients taking medications known to modify bone metabolism (such as bisphosphonates, corticosteroids, etc...)
- •Pregnant or attempting to get pregnant
- •Patients that don't meet the indications for sinus grafting (Existing sinus conditions, sepsis, history of cancer and/or radiation to the oral cavity, use of biphosphonates, pregnancy), or have postoperative complications related to those conditions.
结局指标
主要结局
Histomorphometric proportion of vital bone
时间窗: Six months after sinus bone grafting, after harvesting a bone core biopsy at the time of implant placement
次要结局
未报告次要终点