Stem cells in neonate after delayed cord clamping and umbilical cord milking
Not Applicable
- Registration Number
- CTRI/2019/02/017656
- Lead Sponsor
- DST
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All inborn neonates born via vaginal route, with gestation age >=37 weeks ie term neonate, has cried immediately after birth and has good muscle tone. Infants born on working days, between 9AM-4 PM will be enrolled so that sample for CD 34+ cells is immediately transferred to lab at 4 °C temperature
Exclusion Criteria
Major congenital malformations
Caesarean delivery
Indirect Coombâ??s test positive
Refusal of consent
Any high-risk pregnancy e.g.: Baby limp at birth needing resuscitation, history of intrapartum foetal distress, twins, eclampsia, meconium stained liquor with limp baby, gestation diabetes mellitus, maternal seizures, cord prolapsed, avulsed, placenta previa or abruption.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hematopoietic stem cells/ml of blood, in Delayed cord clamping at 60 seconds after birth <br/ ><br>Hematopoietic stem cells/ml of blood, in umbilical cord milking done within 20 seconds after birth <br/ ><br>Timepoint: Hematopoietic stem cells/ml of blood, in Delayed cord clamping at 60 seconds after birth <br/ ><br>Hematopoietic stem cells/ml of blood, in umbilical cord milking done within 20 seconds after birth <br/ ><br>
- Secondary Outcome Measures
Name Time Method Duration of third stage of labour, postpartum haemorrhage with volume of blood loss <br/ ><br>Placental residual blood volume in DCC vs UCM <br/ ><br>Haematocrit of neonate at 2 hours of life <br/ ><br>Incidence of respiratory distress, neonatal jaundice and polycythaemia in neonate <br/ ><br>Outcome of neonate at discharge from hospital <br/ ><br>Timepoint: At discharge from hospital