effect of probiotics on function of immune system in obesity

Not Applicable

Conditions: overweight and obesity.
Obesity due to excess calories

Registration Number: IRCT201111082709N21

Lead Sponsor: Tehran university of Medical Science

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 75

Inclusion Criteria

inclusion criteria: age of 20-50;BMI= 25-35;interesting in participation in research; without any metabolic disease , CHD, diabetes , without autoimmune disease , cancer; without infection disease in research ;without allergy for cow s milk; no smoking ; no alcoholism; without immune system suppressor drugs 6 mounts before research; no menstrual bleeding ;without any diet 2 mounts before research ;no consumption food supplementation during research

exclusion criteria: metabolic disease , CHD, diabetes , autoimmune disease , cancer; infection disease in research ; allergy for cow s milk; smoking ; alcoholism; immune system suppressor drugs 6 mounts before research; menstrual bleeding; diet 2 mounts before research; lactose deficiency; food supplementation during research; no interesting for participation

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fat percent. Timepoint: after and before of intervention. Method of measurement: BIA method.;BMI. Timepoint: after and before of intervention. Method of measurement: fomula.;IL4-IL9-IL10- IL17- TNF alpha - IFN gama- TGF beta. Timepoint: after and before of intervention. Method of measurement: ELIZA.;Transcription factor of Foxp3 - TGF beta - TNF alpha - GATA3- t-bet -ROR gama IN PBMC. Timepoint: after and before of intervention. Method of measurement: real time- PCR.;Leptin. Timepoint: after and before of intervention. Method of measurement: ELIZA.;HsCRP. Timepoint: after and before of intervention. Method of measurement: ELIZA.

Secondary Outcome Measures