Comparison of probiotic yogurt and ordinary yogurt consumption in patients with chronic heart failure.

Phase 3

Conditions: Chronic heart failure.
Cardiac, heart or myocardial failure NOS
I50.9

Registration Number: IRCT20091114002709N48

Lead Sponsor: Iran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 90

Inclusion Criteria

Age range 30 to 70 years
Having common symptoms of heart failure for at least 1 month
decreased LVEF (=40%)
Being in one of the NYHA classification steps 1-3
Desire to participate in the study and sign a written informed consent

Exclusion Criteria

suffering or having chronic and acute liver (hepatitis B, C, etc.) Diseases and other, diabetes, thyroid disorders, severe renal dysfunction (creatinine more than 300 millimol/liter), pulmonary disease, known inflammatory and autoimmune diseases, Cancer, Rheumatoid Arthritis, Acute Infection
taking any nutritional supplement during the past month
smoking and using narcotic drugs
Lactose intolerance and allergy to dairy products
taking Corticosteroid drug in the last 4 weeks
taking antibiotics over the past 3 months
History of Gastrointestinal Surgery
Taking anti-inflammatory drugs other than low dose of aspirin (one per day)
Having an artificial heart valve
History of rheumatic heart disease
Pregnancy and lactation
taking insulin
body mass index more than 30 Kilogram/meter²

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum pentraxin3. Timepoint: Measurement of serum pentraxin3 at the beginning of the study (before the intervention) and the end of the study (10 weeks after starting probiotic yogurt consumption). Method of measurement: ELISA kit.;Serum oxidized low density lipoprotein. Timepoint: Measurement of serum oxidized low density lipoprotein at the beginning of the study (before the intervention) and the end of the study (10 weeks after starting probiotic yogurt consumption). Method of measurement: ELISA kit.

Secondary Outcome Measures