Association of Carotid Arterial Circumferential Strain With Left Ventricular Function and Hemodynamic Compromise During Off-pump Coronary Artery Bypass Surgery

Completed

• Conditions: Three Vessel Coronary Artery Disease

• Registration Number: NCT01840969
• Lead Sponsor: Yonsei University

Brief Summary

This study is aimed to evaluate the association of common carotid artery circumferential strain with the echocardiographic parameters of left ventricular function and the degree of actual hemodynamic deterioration in patients undergoing multi-vessel off-pump coronary artery bypass with preserved left ventricular ejection fraction.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2011-09
• Primary Completion: 2013-02
• Study Completion: 2013-02
• Status Verified: 2013-04
• Study First Submitted: 2013-04-10
• Study First Submitted QC: 2013-04-25
• Last Update Submitted: 2013-04-25
• Study First Posted: 2013-04-26
• Last Update Posted: 2013-04-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

1. three vessel coronary artery disease
2. sinus rhythm

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Exclusion Criteria

1. New York Heart Association functional class ≥3
2. known pulmonary hypertension
3. known valvular heart disease
4. serum creatinine ≥2.0 mg/dL
5. myocardial infarction within 1 week before the surgery
6. history of cerebral or peripheral arterial occlusive disease

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TTE parameters	1 day before the surgery	TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em

Secondary Outcome Measures

Name	Time	Method
change of intraoperative hemodynamic variables	from after induction of anesthesia, left circumflex artery grafting, and to sternum closure	TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em Carotid circumferential strain : Storage of transverse image of the right CCA at approximately 1cm proximal to the bifurcation, manual trace of luminal-intimal border and automatic tracking by frame-to-frame movement of ultrasound reflections (speckles) Hemodynamic variables: cardiac index and mixed venous oxygen saturation obtained from the pulmonary artery catheter and cardiac output monitoring devices

Trial Locations

Locations (1)

Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of