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Clinical Trials/NCT06316089
NCT06316089
Not yet recruiting
Not Applicable

An Intervention to Improve HIV Pre-exposure Prophylaxis Initiation, Adherence and Linkage to Care for Recently Incarcerated Men Who Inject Drugs.

Rhode Island Hospital0 sites100 target enrollmentJanuary 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hiv
Sponsor
Rhode Island Hospital
Enrollment
100
Primary Endpoint
PrEP initiation
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infection among people who inject drugs (PWID) yet studies suggest that its use is low among this population which is particularly vulnerable to HIV infection. The criminal justice (CJ) system, at the intersection of increased risk of HIV infection and substance use, presents a unique opportunity to engage PWID in HIV prevention care that incudes PrEP. The study will characterize the facilitators and barriers to PrEP initiation, adherence and linkage to care among male PWID that are experiencing incarceration and develop the "PrEPare-for-Release" intervention to promote PrEP initiation, adherence and linkage to care upon release from incarceration into the community.

Registry
clinicaltrials.gov
Start Date
January 2025
End Date
June 2027
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Matthew Murphy

Assistant Professor

Rhode Island Hospital

Eligibility Criteria

Inclusion Criteria

  • At least 18 years of age
  • Incarcerated at the Rhode Island Department of Corrections
  • Identifies as male
  • Reports a history of injection drug use
  • Meets CDC clinical criteria for PrEP use
  • Able to provide written and verbal consent in either English or Spanish

Exclusion Criteria

  • Unable to provide written and/or verbal consent

Outcomes

Primary Outcomes

PrEP initiation

Time Frame: Rapid, within 7 days

Initiation of PrEP usage

Secondary Outcomes

  • Adherence to PrEP(At least 30 days)
  • Linkage to PrEP care in the community(Within 30 days post-incarceration)

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