Online Network Intervention to Increase HIV Pre-exposure Prophylaxis Intention: A Mobile App-based Experiment
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Behavior, Health
- Sponsor
- University of California, Davis
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Change from baseline on Intention to start PrEP
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
HIV pre-exposure prophylaxis (or PrEP) is an effective additional preventative measure for reducing the risk of HIV transmission. To address low levels of uptake, there is a need for public health interventions to increase target populations' awareness and willingness for adopting PrEP. One potential solution may be to incorporate a network intervention, which utilizes the connections between individuals to facilitate health behavior. This project examines how online networks can influence PrEP adoption intentions among gay and bisexual men through a mobile app-based experiment. In this study, participants will be randomly assigned into a social support condition or information-only control. Both conditions will involve an information component consisting messages aimed to address awareness, knowledge, and perceived barriers of PrEP adoption. However, those in the social support condition will also have an online chatting tool where they can discuss topics surrounding PrEP.
The primary objective of this study is to test the effectiveness of the mobile app intervention in increasing participants' knowledge/attitudes/intentions to initiate PrEP.
The secondary objective of this study is to determine the mechanism of the intervention through mediation analyses.
Detailed Description
Roughly 1.7 million people worldwide are infected with HIV each year (UNAIDS, 2017). HIV pre-exposure prophylaxis (or PrEP) refers to taking a daily oral medicine to reduce the risk of contracting HIV. Known by the brand name Truvada or Descovy, PrEP is an effective additional preventative measure for reducing the risk of HIV transmission. To address low levels of uptake, there is a need for public health interventions to increase target populations' awareness and willingness for adopting PrEP. One potential solution may be to incorporate a network intervention, which utilizes the connections between individuals to facilitate health behavior. In particular, online networks can provide anonymous support that transcends geographical boundaries (DeAndrea, 2015). Stigmatized behaviors, such as the adoption of PrEP, may greatly benefit from interventions that utilize online networks. This project examines how online networks can influence PrEP adoption intentions among gay and bisexual men through a mobile app-based experiment. There are several ways in which online networks may influence health; however, social support may serve as the primary mechanism that influences PrEP adoption. In the context of HIV prevention, social support has generally reduced HIV-related risky behaviors (Qiao, Li, \& Stanton, 2014). Thus, it is important to consider social support as a factor than can influence one's intention to adopt PrEP. This field experiment will randomly assign participants into a social support condition or information-only control, and then randomly assign them into homophilous, clustered six-member peer networks. Both conditions will involve an information component consisting messages aimed to address awareness, knowledge, and perceived barriers of PrEP adoption. Social support will be operationalized through an online chatting tool where participants can discuss topics surrounding PrEP. The primary objective of this study is to test the effectiveness of the mobile app intervention in increasing participants' knowledge/attitudes/intentions to initiate PrEP. The secondary objective of this study is to determine the mechanism of the intervention through mediation analyses.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Gay or bisexual male
- •Aged 18 and 35
- •HIV-negative
- •Not on PrEP
- •Using an Android smartphone
Exclusion Criteria
- •Already participating in another HIV-related study.
- •Not able or willing to carry an Android smartphone.
Outcomes
Primary Outcomes
Change from baseline on Intention to start PrEP
Time Frame: Baseline and 1 week
3-item measure based on the Reasoned Action Approach for intention to start PrEP from 1 = "strongly disagree" to 5 = "strongly agree."
Change from baseline on Knowledge of PrEP
Time Frame: Baseline and 1 week
4-items on functional knowledge of HIV pre-exposure prophylaxis. Options include "True," "False," and "Unsure."
Change from baseline on Attitude toward starting PrEP
Time Frame: Baseline and 1 week
7-point semantic differential measure based on the Reasoned Action Approach for attitude to start PrEP with items such as "Good/Bad" and "Useful/Useless."
Secondary Outcomes
- Perceived Social Support(1 week)