The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section

• Conditions: Hypotension; Carbon Dioxide
• Interventions: Procedure: spinal anesthesia

• Registration Number: NCT02032355
• Lead Sponsor: Geng guiqi

Brief Summary

Maternal hypotension is a common side effect after spinal anesthesia for cesarean delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and blood pooling in blocked areas of the body respectively, are main causes of spinal anaesthesia-induced hypotension during Caesarean delivery.

Cardiac output, which has shown to be a better predictor of organ and placental perfusion than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the maternal population.This is largely because of the lack of availability of accurate and reproducible noninvasive measurement techniques. Up to now, preventing hypotension has continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements as markers of cardiovascular status, because these are more easily measured.

Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension during spinal anaesthesia, would also have a positive and significant association.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-01
• Study Start: 2014-01
• Study First Submitted: 2014-01-07
• Study First Submitted QC: 2014-01-09
• Last Update Submitted: 2014-01-09
• Study First Posted: 2014-01-10
• Last Update Posted: 2014-01-10
• Primary Completion: 2014-02
• Study Completion: 2014-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 6

Inclusion Criteria

• full-term gestation (>36 and <41 weeks of gestation) with a singleton pregnancy

Exclusion Criteria

• emergency cases
• placenta praevia
• preeclampsia
• cardiovascular or cerebrovascular disease
• morbid obesity with a BMI≥40
• contraindications to spinal anaesthesia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
hypotension	spinal anesthesia	-

Primary Outcome Measures

Name	Time	Method
value of PetCO2 and changes in artery pressure	up to 4 weeks

Trial Locations

Locations (1)

Obstetrics & Gynecology Hospital, Fudan University; 🇨🇳 Shanghai, Shanghai, China