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Clinical Trials/NCT02032355
NCT02032355
Unknown
Not Applicable

The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section

Geng guiqi1 site in 1 country6 target enrollmentJanuary 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypotension
Sponsor
Geng guiqi
Enrollment
6
Locations
1
Primary Endpoint
value of PetCO2 and changes in artery pressure
Last Updated
12 years ago

Overview

Brief Summary

Maternal hypotension is a common side effect after spinal anesthesia for cesarean delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and blood pooling in blocked areas of the body respectively, are main causes of spinal anaesthesia-induced hypotension during Caesarean delivery.

Cardiac output, which has shown to be a better predictor of organ and placental perfusion than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the maternal population.This is largely because of the lack of availability of accurate and reproducible noninvasive measurement techniques. Up to now, preventing hypotension has continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements as markers of cardiovascular status, because these are more easily measured.

Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension during spinal anaesthesia, would also have a positive and significant association.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
February 2014
Last Updated
12 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Geng guiqi
Responsible Party
Sponsor Investigator
Principal Investigator

Geng guiqi

professor

Fudan University

Eligibility Criteria

Inclusion Criteria

  • full-term gestation (\>36 and \<41 weeks of gestation) with a singleton pregnancy

Exclusion Criteria

  • emergency cases
  • placenta praevia
  • preeclampsia
  • cardiovascular or cerebrovascular disease
  • morbid obesity with a BMI≥40
  • contraindications to spinal anaesthesia

Outcomes

Primary Outcomes

value of PetCO2 and changes in artery pressure

Time Frame: up to 4 weeks

Study Sites (1)

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