The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- value of PetCO2 and changes in artery pressure
研究概览
简要总结
Maternal hypotension is a common side effect after spinal anesthesia for cesarean delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and blood pooling in blocked areas of the body respectively, are main causes of spinal anaesthesia-induced hypotension during Caesarean delivery.
Cardiac output, which has shown to be a better predictor of organ and placental perfusion than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the maternal population.This is largely because of the lack of availability of accurate and reproducible noninvasive measurement techniques. Up to now, preventing hypotension has continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements as markers of cardiovascular status, because these are more easily measured.
Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension during spinal anaesthesia, would also have a positive and significant association.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •full-term gestation (>36 and <41 weeks of gestation) with a singleton pregnancy
排除标准
- •emergency cases
- •placenta praevia
- •preeclampsia
- •cardiovascular or cerebrovascular disease
- •morbid obesity with a BMI≥40
- •contraindications to spinal anaesthesia
结局指标
主要结局
value of PetCO2 and changes in artery pressure
时间窗: up to 4 weeks
次要结局
未报告次要终点
研究者
Geng guiqi
professor
Fudan University
