Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section-A Prospective Observational Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Cairo University
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- correlation between baseline perfusion index and post spinal decrease in systolic blood pressure
Study Overview
Brief Summary
Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients.
The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.
Detailed Description
Abstract Background Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients.
The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.
Methods After approval of ethical committee and written informed consent, fifty Parturients aged between 18- 40 years, ASA I and II with term singleton pregnancies with BMI between 25 &40 admitted for cesarean section under spinal anesthesia were recruited in this prospective, observational study. The primary outcome is the correlation between baseline perfusion index and post spinal hypotension. The secondary outcome is the correlation between BMI and the incidence of hypotension after spinal anesthesia. Heart rate, blood pressure, perfusion index before and after spinal induction using Masimo device, level of sensory block, dose of ephedrine required to correct hypotension, dose of atropine required to correct bradycardia, incidence of nausea, vomiting and shivering were recorded.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Fifty parturient
- •Aged between 18- 40,
- •ASA I and II
- •With term singleton pregnancies
- •With 25 ≥ BMI≤ 40
- •Conducted for cesarean section under spinal anesthesia
Exclusion Criteria
- •Emergency cases,
- •Placenta previa,
- •Preeclampsia,
- •Cardiovascular and cerebrovascular diseases,
- •Patient with contraindication for regional anesthesia
- •Patient with peripheral vascular diseases as DVT.
Outcomes
Primary Outcomes
correlation between baseline perfusion index and post spinal decrease in systolic blood pressure
Time Frame: 24 hours Postoperative
correlation between baseline perfusion index and post spinal decrease in systolic blood pressure
Secondary Outcomes
- correlation between BMI and the incidence of post-spinal hypotension(24 hours Postoperative)
Investigators
Ahmed Abdalla
Professor of Anesthesia &I.C.U and Pain Clinic, Cairo University
Cairo University