Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section

Completed

• Conditions: Perfusion Index Predicts Post-spinal Hypotension

• Registration Number: NCT04186091
• Lead Sponsor: Cairo University

Brief Summary

Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients.

The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.

Detailed Description

Abstract Background Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients.

The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.

Methods After approval of ethical committee and written informed consent, fifty Parturients aged between 18- 40 years, ASA I and II with term singleton pregnancies with BMI between 25 \&40 admitted for cesarean section under spinal anesthesia were recruited in this prospective, observational study. The primary outcome is the correlation between baseline perfusion index and post spinal hypotension. The secondary outcome is the correlation between BMI and the incidence of hypotension after spinal anesthesia. Heart rate, blood pressure, perfusion index before and after spinal induction using Masimo device, level of sensory block, dose of ephedrine required to correct hypotension, dose of atropine required to correct bradycardia, incidence of nausea, vomiting and shivering were recorded.

Study Timeline

• Study Start: 2017-04-01
• Primary Completion: 2018-07-09
• Study Completion: 2018-07-30
• Status Verified: 2019-12
• Study First Submitted: 2019-12-01
• Study First Submitted QC: 2019-12-03
• Last Update Submitted: 2019-12-03
• Study First Posted: 2019-12-04
• Last Update Posted: 2019-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• Fifty parturient
• Aged between 18- 40,
• ASA I and II
• With term singleton pregnancies
• With 25 ≥ BMI≤ 40
• Conducted for cesarean section under spinal anesthesia

Exclusion Criteria

• Emergency cases,
• Placenta previa,
• Preeclampsia,
• Cardiovascular and cerebrovascular diseases,
• Patient with contraindication for regional anesthesia
• Patient with peripheral vascular diseases as DVT.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
correlation between baseline perfusion index and post spinal decrease in systolic blood pressure	24 hours Postoperative	correlation between baseline perfusion index and post spinal decrease in systolic blood pressure

Secondary Outcome Measures

Name	Time	Method
correlation between BMI and the incidence of post-spinal hypotension	24 hours Postoperative	correlation between BMI and the incidence of post-spinal hypotension

Trial Locations

Locations (1)

Ahmed Abdalla Mohamed; 🇪🇬 Cairo, Egypt