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Clinical Trials/NCT04186091
NCT04186091
Completed
Not Applicable

Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section-A Prospective Observational Study

Cairo University1 site in 1 country50 target enrollmentApril 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Perfusion Index Predicts Post-spinal Hypotension
Sponsor
Cairo University
Enrollment
50
Locations
1
Primary Endpoint
correlation between baseline perfusion index and post spinal decrease in systolic blood pressure
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients.

The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.

Detailed Description

Abstract Background Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients. The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient. Methods After approval of ethical committee and written informed consent, fifty Parturients aged between 18- 40 years, ASA I and II with term singleton pregnancies with BMI between 25 \&40 admitted for cesarean section under spinal anesthesia were recruited in this prospective, observational study. The primary outcome is the correlation between baseline perfusion index and post spinal hypotension. The secondary outcome is the correlation between BMI and the incidence of hypotension after spinal anesthesia. Heart rate, blood pressure, perfusion index before and after spinal induction using Masimo device, level of sensory block, dose of ephedrine required to correct hypotension, dose of atropine required to correct bradycardia, incidence of nausea, vomiting and shivering were recorded.

Registry
clinicaltrials.gov
Start Date
April 1, 2017
End Date
July 30, 2018
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Abdalla

Professor of Anesthesia &I.C.U and Pain Clinic, Cairo University

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Fifty parturient
  • Aged between 18- 40,
  • ASA I and II
  • With term singleton pregnancies
  • With 25 ≥ BMI≤ 40
  • Conducted for cesarean section under spinal anesthesia

Exclusion Criteria

  • Emergency cases,
  • Placenta previa,
  • Preeclampsia,
  • Cardiovascular and cerebrovascular diseases,
  • Patient with contraindication for regional anesthesia
  • Patient with peripheral vascular diseases as DVT.

Outcomes

Primary Outcomes

correlation between baseline perfusion index and post spinal decrease in systolic blood pressure

Time Frame: 24 hours Postoperative

correlation between baseline perfusion index and post spinal decrease in systolic blood pressure

Secondary Outcomes

  • correlation between BMI and the incidence of post-spinal hypotension(24 hours Postoperative)

Study Sites (1)

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