Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia

Completed

• Conditions: Monitoring During Deliberate Hypotensive Anesthesia

• Registration Number: NCT03007355
• Lead Sponsor: Cairo University

Brief Summary

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics.

This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study First Submitted: 2016-12-26
• Study First Submitted QC: 2016-12-29
• Study Start: 2017-01
• Study First Posted: 2017-01-02
• Primary Completion: 2017-10
• Study Completion: 2017-12
• Status Verified: 2018-12
• Last Update Submitted: 2018-12-18
• Last Update Posted: 2018-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia

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Exclusion Criteria

• Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
correlation between PPI and T1	start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours	correlation of baseline values of PPI and time required to achieve target mean arterial pressure.