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Clinical Trials/NCT03007355
NCT03007355
Completed
N/A

The Use of Peripheral Perfusion Index as a Predictor for Patient's Response to Deliberate Hypotension During Functional Endoscopic Sinus Surgery A Prospective Observational Study

Cairo University0 sites50 target enrollmentJanuary 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Monitoring During Deliberate Hypotensive Anesthesia
Sponsor
Cairo University
Enrollment
50
Primary Endpoint
correlation between PPI and T1
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics.

This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

Registry
clinicaltrials.gov
Start Date
January 2017
End Date
December 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Abeer Ahmed, MD

Lecturer of Anesthesia - Faculty of Medicine

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia

Exclusion Criteria

  • Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.

Outcomes

Primary Outcomes

correlation between PPI and T1

Time Frame: start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours

correlation of baseline values of PPI and time required to achieve target mean arterial pressure.

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