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Clinical Trials/NCT03319433
NCT03319433
Unknown
Not Applicable

Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section

Paropakar Maternity and Women's Hospital0 sites130 target enrollmentMay 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Spinal
Sponsor
Paropakar Maternity and Women's Hospital
Enrollment
130
Primary Endpoint
Incidence of hypotension
Last Updated
8 years ago

Overview

Brief Summary

Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion. Various methods and agents have been tried in order to address this problem. However, this calamity is far from over.

Perfusion index is one such attempt to address the problem of hypotension by predicting which group of parturient may develop hypotension. This is a type of non-invasive method of assessing the relative vascular tone with the use of pulse oximeter which calculates the ration of pulsatile versus the non-pulsatile component of the blood flow. During normal physiological changes in pregnancy, there is relative loss of vascular tone which predisposes this group of patient to sudden development of hypotension after the sympathetic block due to spinal anesthesia.

Thus, the aim of the study is to use the non-invasive perfusion index data to predict the occurrence of hypotension in a parturient so that helps us to guide fluid and other drug therapy to address the problem of hypotension.

Registry
clinicaltrials.gov
Start Date
May 1, 2018
End Date
November 15, 2018
Last Updated
8 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Paropakar Maternity and Women's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Achyut Sharma

Dr.

Paropakar Maternity and Women's Hospital

Eligibility Criteria

Inclusion Criteria

  • ASA II physical status.
  • Planned for elective LSCS
  • Gestational age \>36 weeks and \<41 weeks

Exclusion Criteria

  • Patient's refusal.
  • Emergency LSCS.
  • Patient's with contraindications to spinal anesthesia
  • Patient with BMI \>40, preeclampsia, placenta praevia.
  • Patients with comorbidities like cerebrovascular or cardiovascular disease, and gestational diabetes.

Outcomes

Primary Outcomes

Incidence of hypotension

Time Frame: 3 months

compare the incidence of hypotension following SAB for LSCS in parturient with or without a high perfusion index.

Secondary Outcomes

  • Perfusion index(3 months)
  • Side-effects(3 months)
  • Systolic blood pressure(3 months)
  • Diastolic blood pressure(3 months)
  • Mean arterial pressure(3 months)

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