NCT05091762招募中不适用
Effect of Physiological Ischemic Training on Patients With Atherosclerosis
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Endothelium dependent vasodilation
研究概览
简要总结
To study whether the resistance training with blood flow obstruction in patients in early atherosclerosis period can produce a beneficial effect on preventing atherosclerosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •LDL > 3.11mmol/l and less than 5.63mmol/l;
- •No serious heart, blood vessel and other related diseases;
- •There were no skeletal and muscular diseases affecting sports training;
- •No regular exercise in the past half year (no more than 2 times a week, no more than 30 minutes each time);
- •Smoking less than 1 pack / year, no history of drinking.
排除标准
- •Haven't other serious heart and vascular diseases other than hyperlipidemia and / or bones and muscles that affect sports training Diseases;
- •Pregnant women and people with disabilities;
- •Other circumstances determined by the researcher not suitable for the study.
研究组 & 干预措施
Exercise group
Experimental
干预措施: exercise (Behavioral)
Hyperlipidemia group
No Intervention
Hyperlipidemia and medication group
No Intervention
Hyperlipidemia and exercise group
Experimental
干预措施: exercise (Behavioral)
Hyperlipidemia and medication and exercise group
Experimental
干预措施: exercise (Behavioral)
Routine treatment group
No Intervention
Routine treatment and exercise group
Experimental
干预措施: exercise (Behavioral)
Blank control group
No Intervention
结局指标
主要结局
Endothelium dependent vasodilation
时间窗: 8 weeks
Percentage of the change
Blood lipid analysis results
时间窗: 8 weeks
Content of total cholesterol, triglycerides, high density lipoprotein and low density lipoprotein
次要结局
- Endothelial repair function(8 weeks)
- The inflammatory state(8 weeks)
研究者
linaicui
Principal Investigator
Nanjing First Hospital, Nanjing Medical University
研究点 (1)
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